Dehydrogenase, which is also known as “DHO” in scientific literature, is basically an enzyme that promotes oxidization in a substrate. This substance oxidises the substrate through a distinct reduction reaction that will transfer one or more hydrides of the substrate to an electron receptor, typically nicotinamide adenine dinucleotide (NAD+) or nicotinamide adenine dinucleotide phosphate (NADP+). The substrate oxidization can also occur in a flavin coenzyme such as flavin adenine dinucleotide (FAD) and flavin mononucleotide.
There are many different kinds of dehydrogenase, including glutamate dehydrogenase, which is an enzyme that can convert glutamate to an α-ketoglutarate and vice versa; pyruvate dehydrogenase, an enzyme that serves an important purose in the tricarboxylic acid cycle by converting pyruvate to acetyl coenzyme A; glucose-6-phosphate dehydrogenase, which is involved in the pentose phosphate pathway; and glyceraldehyde-3-phosphate dehydrogenase, which plays an important role in glycolysis.
The tricarboxylic acid cycle (or TCA cycle)—the series of chemical reactions used by aerobic organisms to generate energy from carbohydrates, fats, and proteins—also uses dehydrogenase for oxidization. The TCA cycle uses isocitrate dehydrogenase (also known as IDH, which catalyzes the third step of the process), oxoglutarate dehydrogenase complex (or α-ketoglutarate dehydrogenase complex), succinate dehydrogenase (or succinate-coenzyme Q reductase, which is found in the inner mitochondrial membrane of many bacterian cells and mammalian mitochondria), and malate dehydrogenase (also known as MDH, which is an enzyme that reverse catalyzes the oxidationof the substance malate to oxaloacetate—a reaction that is part of many metabolic pathways other than the citric acid cycle).
Other types of dehydrogenase include aldehyde dehydrogenase, acetaldehyde dehydrogenase, alcohol dehydrogenase, lactate dehydrogenase, sorbitol dehydrogenase, I-iditol dehydrogenase (ID), isocitrate dehydrogenase (ICD), and polyol dehydrogenase.
This category contains scientific information on dehydrogenase, an enzyme that catalyzes the removal and eventual transfer of hydrogen molecules from a substrate in an oxidation and reduction reaction.
Beaver, Ja; Iezzoni, Af; Ramm, Cw, 1995: Isozyme diversity in sour, sweet, and ground cherry. Theoretical and applied genetics 90(6): 847-852 Thirty-six sour (Prunus cerasus L.), sweet (P. avium L.), and ground cherry (P. fruticosa Pall.) selections were evaluated for seven enzyme systems and principal coordinate analysis was used to examine isozyme divergence among these [...]
Dannel, Frank; Pfeffer, Heidrun; Marschner, Horst, 1995: Isolation of apoplasmic fluid from sunflower leaves and its use for studies on influence of nitrogen supply on apoplasmic pH. Journal Of Plant Physiology. 146(3): 273-273 A centrifugation method for collection of apoplasmic fluid from isolated sunflower leaves has been developed. As indicated by the marker enzymes hexose [...]
Pomazi, Andrea; Hornok, L.; Szecsi, A., 1993: Isoelectric focusing isozyme profiles and taxonomic distances among Fusarium species of the sections Arthrosporiella and Sporotrichiella. Acta Microbiologica Hungarica. 40(1): 71-79 Isozymes from 18 isolates representing seven species of the Fusarium sections Arthrosporiella and Sporotrichiella were compared by isoelectric focusing in polyacrylamide gels. Of the six enzyme systems [...]
Gelwick, Frances P.; Gilliland, Eugene R.; Matthews, William J., 1995: Introgression of the Florida largemouth bass genome into stream populations of northern largemouth bass in Oklahoma. Transactions Of The American Fisheries Society. 124(4): 550-562 Oklahoma streams and reservoirs historically contained only the northern subspecies of largemouth bass Micropterus salmoides salmoides. From 1970 to 1991 Oklahoma [...]
Agius, Loranne; Peak, Matthew, 1993: Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin. Biochemical Journal. 296(3): 785-796 The release of glucokinase from digitonin-permeabilized hepatocytes shows different characteristics with respect to ionic strength and (MgCl-2) from the release of other cytoplasmic enzymes. Release of glucokinase is most rapid at low ionic [...]
Golz, Andrea; Focke, Manfred; Lichtenthaler, Hartmut K., 1994: Inhibitors of de novo fatty acid biosynthesis in higher plants. Journal Of Plant Physiology. 143(4-5): 426-433 The present knowledge of de novo fatty acid biosynthesis in plastids of higher plants is reviewed with respect to its inhibition by various synthetic and natural xenobiotics. Certain enzymatic steps In [...]
Golz, Andrea; Lichtenthaler, Hartmut K., 1994: Inhibition of the plastidic pyruvate dehydrogenase complex in isolated plastids of oat. Zeitschrift Fuer Naturforschung Section C Biosciences. 49(7-8): 421-426 The activity of the plastidic pyruvate dehydrogenase complex (pPDHC) is one source of acetyl-CoA in plastids of higher plants needed for de novo fatty acid biosynthesis. This plastidic enzyme [...]
Magalhaes, J. R.; Huber, D. M.; Tsai, C. Y., 1995: Influence of the form of nitrogen on ammonium, amino acids and N-assimilating enzyme activity in maize genotypes. Journal Of Plant Nutrition. 18(4): 747-763 An understanding of nitrogen (N) interactions with plant growth and metabolism is important in order to increase the efficiency of fertilizer amendments [...]
Guillemin, J. P.; Orozco, M. O.; Gianinazzi Pearson, V.; Gianinazzi, S., 1995: Influence of phosphate fertilization on fungal alkaline phosphatase and succinate dehydrogenase activities in arbuscular mycorrhiza of soybean and pineapple. Agriculture Ecosystems & Environment. 53(1): 63-69 Effects of phosphate fertilization on the physiological activity of arbuscular mycorrhizal infection were studied using fungal succinate dehydrogenase [...]
Hwang, S. G.; Yano, H.; Kawashima, R., 1993: Influence of dietary medium- and long-chain triglycerides on fat deposition and lipogenic enzyme activities in rats. Journal Of The American College Of Nutrition. 12(6): 643-650 The present study investigates fat deposition, variances of fatty acid (Fa) composition, and lipogenic enzyme activities through dietary medium- and long-chain triglyceride [...]